High-Dose
Vitamin B3
Nicotinamide

Pharmaceutical Grade

SKU
4571
High-dose vitamin B3 (niacin) in the form of flush-free, bioactive nicotinamide. An ultra-pure, pharmaceutical grade active ingredient: 500mg vitamin B3 per capsule, suitable for individuals with high vitamin B3 requirements. Vegan, no additives. 120 capsules
  • High-dose niacin: 500mg vitamin B3 per capsule
  • Vitamin B3 (niacin) in the form of highly bioavailable nicotinamide
  • Flush-free, bioactive vitamin B3 in the purest quality
  • For individuals with increased requirements
  • Vitamin B3 reduces tiredness and fatigue and supports energy metabolism, skin and mucous membranes as well as the nervous system and psyche
€9.90
BUNDLE (SAVE 5%)

Delivery : 1–3 business days

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SKU
4571
€13.24 / 100g
In stock

Premium Bioactive Ingredients

  • Vitamin B3 (niacin) in the form of highly bioavailable nicotinamide
  • Nicotinamide: Flush-free, bioactive vitamin B3
  • Directly bioavailable for important metabolic reactions
  • Ultra-pure, vegan active ingredient
  • High-dose niacin: 500mg vitamin B3 per capsule

How are we different?

Vitamin B3 exists in various chemical forms. The most common form is nicotinic acid, which serves as the starting point for the metabolism of vitamin B3 and must be converted into an active coenzyme form in a multi-stage process. Nicotinic acid has the distinctive disadvantage that, in large doses, it can cause niacin flush: a sudden expansion of the blood vessels that causes itching and reddening of the skin.

Nicotinamide (niacinamide) can be considered the next stage of the niacin metabolic process. It can be easily converted into the coenzymes NAD and NADP and, even in higher doses, is not likely to cause a niacin flush. The direct intake of these enzymes, however, is not practical in a supplement since they largely cannot survive the gastrointestinal system and would need to be taken in very large doses.

For these reasons we offer vitamin B3 in the form of flush-free nicotinamide, which is not only a very potent form of B3, but also a form that can be easily converted into NAD coenzymes. The raw material used is high quality and particularly pure.

For the capsule shells we use custom-made HPMC capsules that, unlike most other HPMC and pullulan capsules on the market, are 100% free from controversial additives such as carrageenans and PEG. We then package this product in environmentally friendly amber glass.

truecleanlabel

  • Premium active ingredients in their purest form
  • Sourced directly from the world’s best producers
  • Our select raw materials are the basis of all our formulations
  • Complete avoidance of all unnecessary additives and adjuvants
  • Exclusive use of valuable natural ingredients for additives
  • We voluntarily declare all ingredients
  • All extractions performed without the use of chemical solvents
  • Custom production when necessary, in order to achieve the highest possible level of purity
  • Independent laboratory testing available on product pages
  • Raw materials sourced only from premium suppliers who are committed to fair working conditions
  • Amber glass and compostable pouches used for packaging
  • Vegan capsule shells, free from PEG and carrageenans
  • Packaged in the EU according to HACCP, GMP and ISO 22000:2018 standards
  • Stored in non-toxic containers
  • Shipped in mineral oil-free boxes
  • All products guaranteed 100% free from magnesium stearate, silicon dioxide, nanoparticles (no legal opportunism), genetic engineering, artificial colours and flavours, titanium dioxide and added sugar & sweeteners

Effects

Vitamin B3

Vitamin B3 (niacin) is a precursor of nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP), two central coenzymes in cell metabolism involved in over 450 redox reactions. NAD is required for countless body reactions as an energy transmitter and is an essential component of the respiratory chain. Vitamin B3 is therefore essential for the body's energy supply and is present in various forms in virtually all body tissue.

NAD also enables the formation of sirtuins and ADP-ribosyl polymerase, two chemical messengers which control countless fundamental cellular processes. The combined effects of vitamin B3 therefore influence almost the entire metabolism.

Vitamin B3 is involved in energy production as well as the metabolism of carbohydrates, fats and amino acids. Vitamin B3 regulates numerous regeneration and repair processes, including of the skin and mucous membranes.

A sufficient supply of niacin is also vital for the nervous system because of the role it plays in the formation of important chemical messengers.

Nicotinamide/Niacinamide: Bioavailable B3 without the Typical Vitamin B3 Flush

Nicotinic acid must be converted into active coenzymes over several steps within vitamin B3 metabolism. In larger quantities, the intake of nicotinic acid leads to a niacin flush, which is defined by a sudden dilation of blood vessels accompanied by strong tingling and reddening of the skin. Nicotinamide, or niacinamide, is the compound from the next stage of vitamin B3 metabolism. This form metabolises easily into NAD and NADP and, even with high doses, only causes flushing in those with impaired B3 metabolism.

Health Benefits of Vitamin B3

According to the European Food Safety Authority (EFSA), vitamin B3 contributes to:

  • Normal energy metabolism
  • Normal functioning of the nervous system
  • Normal mental function
  • Maintaining normal mucous membranes
  • Maintaining normal skin
  • Reducing tiredness and fatigue

Dosage

Recommended Dosage

Take 1 capsule (250mg vitamin B3) daily with 200ml water.

Daily Requirements

The recommended daily intake of vitamin B3 for adults is at least 13-17mg.

An individual's B3 requirements can be increased due to alcohol consumption, malnutrition, intake of certain medications and reduced absorption capacity due to metabolic and intestinal diseases. It can also be increased during pregnancy and breastfeeding.

Food Supplement

Do not exceed the recommended dose. Food supplements cannot replace a balanced and varied diet. Keep out of reach of children.

Storage

Store in a cool, dry place away from direct sunlight and heat.

Contents

Ingredients: Vitamin B3 (in the form of Nicotinamide).
Capsule shells: Hydroxypropyl Methylcellulose.
Contains: 120 capsules

Ingredients/Capsule % NRV*
Vitamin B3 500mg 3,125%

* Nutrient Reference Value

Per capsule: 500mg vitamin B3
In total: 60g vitamin B3

Cofactors

All eight essential B vitamins work together. Numerous metabolic processes in the body require them; they can only achieve optimal functionality if each vitamin is in sufficient supply. Therefore, in many cases, it makes sense to supplement these vitamins together.

Product Details

German Pharmaceutical Number (PZN) 15423025
Production In-house production in Europe, bottling and encapsulation in the EU according to HACCP, GMP/ISO 22000:2018 standards
Finished products packaged in amber glass jars and stored in non-toxic containers
Shipping in mineral oil-free boxes
Capsules Plant-based cellulose (HPMC). Vegan
Premium HPMC quality: Free from controversial additives such as carrageenans and PEG
Packaging Amber glass jar to protect against light and oxidation (free from plasticisers and BPA)
To Reuse Remove product label by soaking the jar in warm water for 5 minutes. Glue residue can be removed with dish soap.

Sunday Natural

Our Philosophy

For thousands of years, cultures all over the world have been using medicinal plants and nutritious foods to naturally foster and maintain vitality and good health.

With our products, we try to emulate this ancient wisdom as much as possible.

Consequently, our philosophy is simple: everything we do meets the highest standards of quality and purity; our focus is on organic and natural ingredients.

We follow this philosophy with meticulous care on all levels and down to every last detail.

Learn more.

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