- MH3A® formula: bioactive vitamin B12 as methylcobalamin, hydroxocobalamin and adenosylcobalamin
- All three natural forms of vitamin B12
- 2 active coenzyme forms with high bioavailability
- 5 different premium B12 active ingredients from the EU
- Folate Complex Ultra: three premium folate active ingredients
- Two L-methylfolate active ingredients (L-5-MTHF)
- Folate as L-5-MTHF, the directly active coenzyme form with enhanced bioavailability
- Full spectrum of natural folates from lemon peel
- An ideal ratio of vitamin B12 to folate
- Tablets: for improved absorption via the oral mucosa (sublingual absorption)
- Direct, rapid absorption into the bloodstream, bypassing gut-related absorption issues
- High-dose: 1000µg B12 + 400µg folic acid per tablet
- Highly effective L-methylfolate support across all metabolic pathways
- Natural tablets made from valuable guar bean fibre, GMO-free
Vitamin B12 MH3A® + Folate
1000µg + 400µg Ultra
Vitamin B12 + Folate Complex with 1000µg B12 and 400µg folate to support daily requirements. Premium MH3A® formula featuring three natural B12 forms and a comprehensive L-methylfolate complex (L-5-MTHF). 120 tablets
- MH3A® formula with 5 natural forms of vitamin B12
- Bioactive forms: methylcobalamin, adenosylcobalamin and hydroxocobalamin
- Comprehensive complex of three bioactive L-methylfolate active ingredients
- Folate sourced from lemon peel, L-5-MTHF glucosamine salt & Magnafolate® Pro
- 1000µg B12 and 400µg folate per tablet to support daily requirements
- Tablets based on guar bean fibre for sublingual absorption
- Dissolve 1 tablet daily under the tongue or take with water
€11.90
Premium Bioactive Ingredients
How are we different?
Not all forms of vitamin B12 and folate are equally effective. Conventional supplements often contain only synthetic forms of folic acid and vitamin B12, which the body must first convert into their biologically active forms before they can be utilised. Sunday Natural Vitamin B12 MH3A® plus Folate Complex Ultra delivers the full spectrum of bioactive, natural forms for both vitamins.
Conventional combination supplements of B12 and folate typically provide just one active ingredient per vitamin. Within our body and in natural foods, however, both occur in several active forms. Each form has a different effect and is absorbed through partially distinct metabolic pathways, meaning the optimal B12 or folate form can vary from person to person. By combining two premium active ingredient complexes containing all the active, natural B12 and folate cofactors, we ensure ideal absorption of both vitamins.
As the B12 pioneer who first introduced it, our Vitamin B12 MH3A® formula delivers vitamin B12 the way it naturally occurs in food, unlike many conventional B12 supplements: as a combination of all three natural, bioactive forms of vitamin B12 in optimal synergy. Each of these three forms fulfils distinct roles in the body and has its own area of focus. Our MH3A® formula contains all three forms of vitamin B12 in an equal, balanced ratio across five B12 active ingredients, providing comprehensive all-round support, mirroring how all three forms are always found together, both in the body and in nature's own food sources. On the market, almost all available supplements contain only one of the three B12 active ingredients: methylcobalamin, hydroxocobalamin or adenosylcobalamin.
In our Folate Complex Ultra formula, we've combined three premium folates for exceptional folate diversity. The two most bioactive L-methylfolates: the glucosamine salt and the highly bioavailable calcium salt. Both deliver 99.9% pure L-methylfolate and complement one another through quick, effective absorption of bioactive L-5-MTHF via distinct metabolic pathways. As a third ingredient, lemon peel extract provides the full spectrum of natural folates, offering seamless, comprehensive support modelled on nature itself. The glucosamine salt is a form in which methylfolate is bound to glucosamine to stabilise it, ensuring optimal shelf life and efficacy. Glucosamine is itself a valuable, natural component of various body tissues, adding further benefit to the overall effect. This form stands out for its previously unmatched bioavailability and can be utilised directly by the body. Owing to its exceptional purity, high stability and outstanding bioavailability, this glucosamine salt ranks among the two most valuable and effective forms of L-methylfolate available. The second premium active ingredient is highly bioavailable L-methylfolate as L-5-methyltetrahydrofolate, bound to a calcium salt in a special, particularly effective crystalline form. This ensures an extremely high absorption rate of the active ingredient L-5-MTHF. As a result, during first-pass absorption, the initial uptake step, 76% of the active ingredient can be absorbed into the bloodstream, where it's even able to cross the blood-brain barrier. With a minimum purity of 99.9% of the active (6S) isomer of L-methylfolate and its high stability, it stands as one of the two unrivalled premium forms of L-methylfolate.
Dissolving the tablets in the mouth offers the advantage that the vitamins can be absorbed directly through the oral mucosa via passive diffusion. This bypasses gut-related absorption issues and significantly increases bioavailability. Via this route, the vitamins also enter the bloodstream directly, without first having to pass through the liver, as would be the case with intestinal absorption.
Our premium tablets are made using natural guar bean fibre as their base. We entirely avoid the use of pressing aids such as magnesium stearate or coatings with sweeteners, colourings or gelatine.
Effects
Vitamin B12 (Cobalamin)
Vitamin B12 fulfils a number of important functions in the body: it can help to reduce tiredness and fatigue and maintain a normal energy metabolism; it contributes to the normal functioning of the psyche, immune and nervous systems; supports the formation of red blood cells; and is beneficial for normal homocysteine metabolism. The body also needs vitamin B12 for cell division.
Vitamin B12 acts as a so-called coenzyme in the body, meaning it is necessary for certain enzymes to fulfil their tasks. The associated reactions are directly dependent on vitamin B12 and cannot take place without it.
Vitamin B12 MH3A® Formula
Vitamin B12 exists in different chemical forms, each with different functions within the body. The natural forms of vitamin B12 that can be readily absorbed by the body are described as "bioactive coenzymes." Synthetic forms of vitamin B12 such as cyanocobalamin must be first coverted into a natural form by the body in order to be effective, which is why we use naturally bioactive vitamin B12.
The biologically active coenzyme forms of vitamin B12 in the body are called methylcobalamin and adenosylcobalamin. Both act at different places and in completely different reactions, which is why humans need both forms of vitamin B12 and can also convert them into each other. Methylcobalamin is active in the cytoplasm as a part of the methylation cycle, which has a broad impact on various aspects of our health such as blood formation, brain health, and the nervous system. Adenosylcobalamin, on the other hand, is active within the mitochondria – the "powerhouses" of cells – where it is part of the citric acid cycle, considered the main metabolic cycle for energy production.
Hydroxocobalamin is another natural form of vitamin B12 that can be found in many food products. Most of the vitamin B12 in the blood is in the form of hydroxocobalamin. Hydroxocobalamin binds particularly well to vitamin B12 transport molecules and is therefore excreted less quickly; as a result, it is considered the B12 with the best repository properties. Hydroxocobalamin can be easily converted by the body into the active coenzyme forms as needed.
Vitamin B9 Folate (Folic Acid)
Folate, also known as vitamin B9, is involved in a variety of important body functions. This essential vitamin contributes to energy metabolism, it can reduce fatigue and tiredness and it supports the immune system as well as mental functioning. It is required for haematosis, cell division, homocysteine metabolism and forming amino acids. Folate also plays a role in the growth of maternal tissue during pregnancy.
Synthetic folic acid must first be converted into folate in order to be bioactive. This conversion cannot always proceed in the body without issue, as a number of cofactors and enzymes are necessary for it to occur. The optimal, biologically active form of folate is called L-methylfolate (or, more precisely, L-5-methyltetrahydrofolate, or L-5-MTHF). L-methylfolate is an important methyl donor and an essential component of the methylation cycle.
According to the European Food Safety Authority (EFSA):
Vitamin B12 contributes to:
- normal energy metabolism
- normal functioning of the nervous system
- normal homocysteine metabolism
- normal mental function
- normal formation of red blood cells
- normal function of the immune system
- reduction of tiredness and fatigue
- cell division
According to the European Food Safety Authority (EFSA):
Folate contributes to:
- the growth of maternal tissue during pregnancy
- normal amino acid synthesis
- normal hemopoiesis
- normal homocysteine metabolism
- normal cognitive function
- normal immune system functioning
- the reduction of tiredness and fatigue
- cell division
Dosage
Directions
Take 1 tablet daily with 200ml of water half an hour before a meal, or dissolve in the mouth with sufficient water.
Note: Our guar gum tablets are deliberately formulated to dissolve very slowly in the mouth. This allows for improved absorption (sublingual absorption). It's advisable to let the tablets remain in contact with the oral mucosa for as long as possible without swallowing. If needed, the tablets can either be chewed or swallowed with plenty of water.
Contraindications
Not suitable for children under the age of 7.
Daily Requirements
The German Nutrition Society (DGE) recommends a minimum intake of 4µg vitamin B12 per day for adults.
According to European authorities, the official daily folic acid requirement for adults is 200µg. The German Nutrition Society (DGE), however, recommends a daily average of 300µg for adults. The DGE notes an increased requirement for individuals who are pregnant (550µg) or breastfeeding (450µg).
B12 Intake
The human body can only absorb a portion of the vitamin B12 found in food and supplements: only about 1–2µg of vitamin B12 can be absorbed at a time via the intrinsic factor, a special protein, with a further 1% absorbed via passive diffusion through the intestine. Calculating total B12 absorption therefore requires taking both of these factors into account. Note: By distributing intake of B12 throughout the day, absorption via the intrinsic factor can be maximised.
According to this formula, Sunday Natural MH3A® 1000µg yields a calculated intake of 10–12 µg of vitamin B12 per tablet.
Food Supplement
Do not exceed the recommended daily intake. Food supplements are not a substitute for a balanced, varied diet and healthy lifestyle. Keep out of reach of young children.
Storage
Store in a cool, dry place away from direct sunlight and heat.
Contents
Ingredients: Lemon Peel Extract, Guar Bean Fibre, Hydroxocobalamin Sulphate, 5-MTHF Glucosamine, Methylcobalamin, 5-Deoxyadenosylcobalamin, Hydroxocobalamin Acetate, Calcium L-Methylfolate, Hydroxocobalamin Chloride.
Note: The enclosed cotton wool is made from 100% natural, absorbent cotton fibres and produced without optical brighteners. It serves as packing material to protect the tablets. The number of tablets corresponds to the information on the packaging.
| Nutrition Information Per Tablet | %NRV* | |
| Vitamin B12 (MH3A®) | 1000µg | 40,000 |
| Folate (as L-MTHF) | 400µg | 200 |
* Nutrient Reference Value
vegan
fructose free
lactose free
gluten free
non-GMO
bioactive
True Clean Label
amber glass
soya free
Cofactors
All eight essential B vitamins work very closely together in numerous metabolic processes in the body. In many cases it therefore makes sense to take the vitamins together.
Laboratory Tests
The purity of our formulas is important to us. This is why we have both our raw ingredients as well as our finished products extensively tested by independent laboratories to confirm purity and active ingredient content. Here, we have provided the results of some of the tests carried out on this product.
