Vitamin B12 + Folic Acid
MH3A® + Quatrefolic®
1,000µg + 400µg

Bioactive

SKU
4394
1,000µg of vitamin B12 per capsule in the form of all three natural cobalamins and 5 different B12 active ingredients (MH3A® formula). Plus 400µg folate in the form of Quatrefolic® (L-methylfolate/L-5-MTHF). Bioactive and 100% natural. Vegan, non-GMO, no chemical additives. Produced in the EU. 120 mini capsules
  • MH3A® formula: harmonious mixture of 5 premium B12 active substances
  • Bioactive vitamin B12 in the form of methylcobalamin, hydroxocobalamin and adenosylcobalamin
  • 2 active coenzyme forms with high bioavailability
  • Patented L-methylfolate (L-5-MTHF) Quatrefolic®
  • Full 1000 µg B12 per capsule plus 400 µg bioactive folic acid
  • Vitamin B12 for homocysteine metabolism, emotional function, immune system, reduction of tiredness and fatigue
  • Vitamin B12 for energy metabolism, the central nervous system, the production of red blood cells
  • Folate supports the growth of maternal tissue during pregnancy, amino acid synthesis and haematosis - Natural acacia fibre as the only other ingredient
  • High-quality, natural filler: acacia fibre cultivated without the use of plant protection products
€15.90
120 capsules
BUNDLE (SAVE 15%)

Delivery : 1–3 business days

Incl. VAT, excl. Shipping

SKU
4394
€548.28 / 1kg
In stock

Premium Bioactive Ingredients

  • MH3A® formula: bioactive vitamin B12 in the form of methylcobalamin, hydroxocobalamin and adenosylcobalamin
  • All three natural, bioactive forms of vitamin B12.
  • 2 active coenzyme forms with high bioavailability
  • 5 different B12 active substances
  • Patented L-methylfolate (L-5-MTHF) Quatrefolic®
  • Folate as L-5-MTHF - the directly active coenzyme form with increased bioavailability
  • 99.9% pure L-5-methyltetrahydrofolate
  • Ideal balance between vitamin B12 and folate
  • Full 1000 µg B12 per capsule plus 400 µg bioactive folic acid
  • High-quality, natural filler: acacia fibre cultivated without the use of plant protection products

How are we different?

Not all forms of vitamin B12 and folic acid show the same effectiveness. Common dietary supplements often contain only synthetic forms of folic acid and vitamin B12. These must first be transformed into the biologically active forms in the body before they can be utilised. Sunday Natural Vitamin B12 MH3A® plus Quatrefolic® provides the bioactive and natural forms of both vitamins.

Conventional vitamin B12 and folic acid supplements usually provide only one active ingredient per vitamin. In our bodies and natural foods, however, both occur in different active forms. All forms show a different effect and enter the body partly via different metabolic pathways, so that it is individually different which B12 or folate form is best absorbed. We combine two high-quality active ingredient complexes of all active and natural B12 and folic acid cofactors to ensure ideal absorption of both vitamins.

As a pioneer in B12 products, our innovative Vitamin B12 MH3A® formula supplies B12 in the natural forms that the body also obtains from healthy foods: as a combination of all three natural and bioactive B12 compounds. These three MHA (methylcobalamine, hydroxocobalamin, and adenosylcobalamin) forms each fulfil unique functions in the body and have different effect profiles. Our MH3A® formula contains all three in a balanced ratio and thus delivers an ideal and well-rounded supply of vitamin B12- because in nature, too, all three forms are always found together in our bodies as well as in food. On the market, there are almost exclusively supplements with only one of the three B12 active ingredients: methylcobalamin, hydroxocobalamin or adenosylcobalamin.

We use L-methylfolate in the form of Quatrefolic®, a premium active ingredient, which is almost completely pure and guaranteed to contain more than 99.9% bioactive folate in the L-methylfolate form. Quatrefolic® is a patented active ingredient, in which methylfolate binds to purely vegan glucosamine derived from fermentation. This is how it becomes stable and safeguards an optimal shelf life as well as efficacy. Glucosamine is a valuable part of various body tissues and an additional asset for the overall effect of the product. Quatrefolic® is characterised by its unique bioavailability and can be directly utilised by the body. It is characterised by its high quality and is one of the two most efficient forms of L-methylfolate thanks to its extreme purity, high stability, and excellent bioavailability.

The geometric variant R-methylfolate, which exists along with L-methylfolate, cannot be utilized by the body. Many active ingredients contain a combination of these two forms as they appear together in most production processes. Common forms of methylfolate can contain up to 50% of these ineffective variants.

The only additional ingredient is premium acacia fibre from pesticide-free cultivation, used as a natural bulking agent. In contrast to conventional synthetic fillers such as microcrystalline cellulose, which is mixed with nano-particles, we use a natural, fibre-rich foodstuff. Our acacia fibre comes from climate-neutral, sustainable, resource-conserving, fair cultivation.

For the capsule shells we use custom-made HPMC capsules that, unlike most other HPMC and pullulan capsules on the market, are 100% free from controversial additives such as carrageenans and PEG. We then package this product in environmentally friendly amber glass.

truecleanlabel

  • Premium active ingredients in their purest form
  • Sourced directly from the world’s best producers
  • Our select raw materials are the basis of all our formulations
  • Complete avoidance of all unnecessary additives and adjuvants
  • Exclusive use of valuable natural ingredients for additives
  • We voluntarily declare all ingredients
  • All extractions performed without the use of chemical solvents
  • Custom production when necessary, in order to achieve the highest possible level of purity
  • Independent laboratory testing available on product pages
  • Raw materials sourced only from premium suppliers who are committed to fair working conditions
  • Amber glass and compostable pouches used for packaging
  • Vegan capsule shells, free from PEG and carrageenans
  • Packaged in the EU according to HACCP, GMP and ISO 22000:2018 standards
  • Stored in non-toxic containers
  • Shipped in mineral oil-free boxes
  • All products guaranteed 100% free from magnesium stearate, silicon dioxide, nanoparticles (no legal opportunism), genetic engineering, artificial colours and flavours, titanium dioxide and added sugar & sweeteners

Effects

Vitamin B12 (Cobalamin)

Vitamin B12 takes on a variety of important functions in the organism. These include helping to reduce tiredness and fatigue and maintaining a normal energy metabolism. It contributes to a normal function of the psyche, immune and nervous system, it supports the formation of red blood cells and is beneficial for a normal homocysteine metabolism. Furthermore, the body needs vitamin B12 cell division. Vitamin B12 acts as a so-called coenzyme in the body. This means that vitamin B12 is necessary for certain enzymes in our body to fulfil their tasks. The related processes are directly dependent on vitamin B12 and cannot take place without the vitamin.

VITAMIN B12 MH3A® Formula

Vitamin B12 exists in different chemical forms, each with different functions within the body. The natural forms of vitamin B12 that can be readily absorbed by the body are described as "bioactive coenzymes". Synthetic forms of Vitamin B12 such as cyanocobalamin must be first coverted into a natural form by the body in order to be effective, which is why we use naturally bioactive Vitamin B12.

The biologically active coenzyme forms of vitamin B12 in the body are called methylcobalamin and adenosylcobalamin. Both act at different places and in completely different reactions, which is why humans need both forms of vitamin B12 and can also convert them into each other. Methylcobalamin is active in the cytoplasm as a part of the methylation cycle, which has a broad impact on various aspects of our health such as blood formation, brain health, and the nervous system. Adenosylcobalamin, on the other hand, is active within the mitochondria—the "powerhouses" of cells—where it is part of the citric acid cycle, considered the main metabolic cycle for energy production. Hydroxocobalamin is another natural form of vitamin B12 that can be found in many food products. Most of the vitamin B12 in the blood is in the form of hydroxocobalamin. Hydroxocobalamin binds particularly well to vitamin B12 transport molecules and is therefore excreted less quickly; as a result, it is considered the B12 with the best depot properties. Hydroxocobalamin can be easily converted by the body into the active coenzyme forms as needed.

Vitamin B9 Folate 

Folate, also known as vitamin B9, is involved in a variety of important body functions in the organism. This essential vitamin fulfils numerous important tasks in cell metabolism. It also contributes to the functioning of energy metabolism, can reduce fatigue and tiredness and supports the immune system as well as mental functioning. It is needed for haematosis, cell division, homocysteine metabolism and forming amino acids. Folate also plays a role in the growth of maternal tissue during pregnancy.

Synthetic folate must be first converted into active folate by the body before taking effect. Folate conversion can be especially difficult for those with inherited metabolic disorders, because it requires various cofactors and enzymes. The naturally active form of folate is known as L-methylfolate (L-5-methyltetrahydrofolate or L-5-MTHF). L-methylfolate is an important methyl donor and an essential part of the methylation cycle.

The patented premium active ingredient Quatrefolic® provides 99.9% pure L-5-methyltetrahydrofolate.

Health Benefits of Vitamin B12 According to the European Food Safety Authority (EFSA):

Vitamin B12 contributes to:

  • Normal energy-yielding metabolism
  • Normal functioning of the nervous system
  • Normal homocysteine metabolism
  • Normal psychological function
  • Normal red blood cell formation
  • The normal function of the immune system
  • The reduction of tiredness and fatigue
  • Vitamin B12 has a role in the process of cell division

Health Benefits of Folate (Vitamin B9) According to the European Food Safety Authority (EFSA):

Folate contributes to:

  • The growth of maternal tissue during pregnancy
  • Normal amino acid synthesis
  • Normal haematosis
  • Normal homocysteine metabolism
  • Normal mental function
  • Normal functioning of the immune system
  • Reducing tiredness and fatigue
  • Cell division

Dosage

Recommended Dosage

Take 1 capsule daily with 200ml water 30 minutes before a meal.

Daily Requirements

The German Nutrition Society (DGE) recommends a minimum of 3µg vitamin B12 per day for adults.

According to European authorities, the official daily folic acid requirement for adults is 200µg. The German Nutrition Society (DGE), however, recommends a daily average of 300µg for adults. The DGE notes an increased requirement for individuals who are pregnant (550µg) or breastfeeding (450µg).

B12 Absorption

The human body can only absorb small quantities of vitamin B12 through food and supplements. Only approximately 1-2µg vitamin B12 per dosage can be actively absorbed through the special "intrinsic factor" protein and a further 1% of the dosage is absorbed through passive diffusion. The total supplement intake is estimated based on the combination of these two factors.

According to this calculation, Sunday Natural Vitamin B12 MH3A® Formula+ Folate 400 enables an intake of 6-8µg Vitamin B12 per capsule.

Food Supplement

Do not exceed the recommended dose. Food supplements cannot replace a balanced and varied diet. Keep out of reach of children.

Storage

Store in a cool, dry place away from direct sunlight and heat.

Contents

Ingredients: Vitamin B12 (in the form of Methylcobalamin, Hydroxocobalamin and Adenosylcobalamin), L-Methylfolate, Prebiotic Acacia Fibre.
Capsule shells: Hydroxypropyl Methylcellulose.
Contains: 120 mini-capsules

Ingredients per Capsule % NRV*
 Vitamin B12 1,000µg 40,000 %
of which methylcobalamin   333µg 13,333 %
of which hydroxocobalamin    333µg 13,333 %
of which adenosylcobalamin   333µg 13,333 %
Folic Acid (Quatrefolic®) 400µg 200%

* Nutrient Reference Value

Cofactors

All eight essential B vitamins work together. Numerous metabolic processes in the body require them; they can only achieve optimal functionality if each vitamin is in sufficient supply. Therefore, in many cases, it makes sense to supplement these vitamins together.

Product Details

German Pharmaceutical Number (PZN) 17273920
Origin All ingredients from the EU
Production In-house production in Europe, bottling and encapsulation in the EU according to HACCP, GMP and ISO 22000:2018 standards
Finished products packaged in amber glass jars and stored in non-toxic containers
Shipping in mineral oil-free boxes
Capsule Shells Plant-based cellulose (HPMC). Vegan
Premium HPMC quality: Free from controversial additives such as carrageenans and PEG
Packaging Amber glass jar to protect against light and oxidation (free from plasticisers and BPA)
To Reuse Remove product label by soaking the jar in warm water for 5 minutes. Glue residue can be removed with dish soap.

Laboratory Tests

The purity of our formulas is important to us. This is why we have both our raw ingredients as well as our finished products extensively tested by independent laboratories to confirm purity and active ingredient content. Here, we have provided the results of some of the tests carried out on this product.

Sunday Natural

Our Philosophy

For thousands of years, cultures all over the world have been using medicinal plants and nutritious foods to naturally foster and maintain vitality and good health.

With our products, we try to emulate this ancient wisdom as much as possible.

Consequently, our philosophy is simple: everything we do meets the highest standards of quality and purity; our focus is on organic and natural ingredients.

We follow this philosophy with meticulous care on all levels and down to every last detail.

Learn more.

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