Bioactive B Complex
With Cofactors


High-dose B complex specially designed for individuals seeking to avoid overmethylation. Supplies non-methylated, bioactive B vitamins plus taurine, glycine and glutamine to boost glutathione synthesis. Including vitamin B12 in the form of adenosylcobalamin, vitamin B6 in the form of active P5P and choline in the form of active CDP-choline. Vegan, no additives. 90 capsules
  • Premium B complex formulated without methyl donors or folic acid: consists exclusively of non-methylated B vitamins
  • 7 B vitamins, 2 cofactors and 3 amino acids, all optimally bioavailable
  • Vitamin B12 in the form of active adenosylcobalamin, vitamin B6 in the form of directly bioactive P5P and vitamin B2 in the form of R5P/FMN
  • B vitamins support energy and iron metabolism, amino acid synthesis, mucous membranes, heart function, the nervous system, skin, hair and psyche as well as contribute to cell division and the protection of cells against oxidative stress
  • Cofactors: active CDP-choline and myo-inositol
  • Taurine, L-glycine and L-glutamine, either pharmaceutical grade or derived from fermentation, to increase glutathione synthesis
  • No additives
  • Ultra-pure, vegan capsule shells made from plant-based cellulose (HPMC), free from PEG and carrageenans
90 capsules

Delivery : 1–3 business days

Incl. VAT, excl. Shipping

€227.46 / 1kg
In stock

Premium Bioactive Ingredients

  • Premium B complex specially designed to prevent overmethylation
  • Non-methylated B vitamins, no folic acid (vitamin B9)
  • 7 B vitamins, 2 cofactors and 3 amino acids
  • Directly bioactive forms
  • Vitamin B12 in the form of active adenosylcobalamin
  • Vitamin B6 in the form of directly bioactive P5P
  • Vitamin B2 in the form of R5P/FMN
  • Cofactors: active CDP-choline and myo-inositol
  • Taurine, L-glycine and L-glutamine to increase glutathione synthesis
  • Vegan amino acids, either pharmaceutical grade or derived from fermentation
  • Optimally bioavailable ingredients

How are we different?

Our Bioactive B Complex Sensitive is specially designed to prevent overmethylation while supplying the entire B complex (except vitamin B9). It does not contain folate, betaine or any methylated B vitamins; vitamin B12 is included not as methylcobalamin, but rather as adenosylcobalamin, while folate and betaine are completely omitted due to their strong stimulating effect on the methylation cycle.

In addition to the B vitamins, this complex also includes the important cofactors CDP-choline (formerly vitamin B4) and myo-inositol (formerly vitamin B8), as well as a special mixture of three vegan amino acids (either pharmaceutical grade or derived from fermentation): taurine, L-glycine and L-glutamine.

For the capsule shells we use custom-made HPMC capsules that, unlike most other HPMC and pullulan capsules on the market, are 100% free from controversial additives such as carrageenans and PEG. We then package this product in environmentally friendly amber glass.


  • Premium active ingredients in their purest form
  • Sourced directly from the world’s best producers
  • Our select raw materials are the basis of all our formulations
  • Complete avoidance of all unnecessary additives and adjuvants
  • Exclusive use of valuable natural ingredients for additives
  • We voluntarily declare all ingredients
  • All extractions performed without the use of chemical solvents
  • Custom production when necessary, in order to achieve the highest possible level of purity
  • Independent laboratory testing available on product pages
  • Raw materials sourced only from premium suppliers who are committed to fair working conditions
  • Amber glass and compostable pouches used for packaging
  • Vegan capsule shells, free from PEG and carrageenans
  • Packaged in the EU according to HACCP, GMP and ISO 22000:2018 standards
  • Stored in non-toxic containers
  • Shipped in mineral oil-free boxes
  • All products guaranteed 100% free from magnesium stearate, silicon dioxide, nanoparticles (no legal opportunism), genetic engineering, artificial colours and flavours, titanium dioxide and added sugar & sweeteners


B Vitamins

The B vitamin group includes eight water-soluble essential nutrients: vitamins B1, B2, B3, B5, B6, B12, biotin and folic acid. Unlike many vitamins, B vitamins cannot be stored in the body over a long period of time and must therefore be obtained daily through food. The only exception is vitamin B12, which can be stored in the liver.

It is crucial to ensure a balanced intake of all B vitamins due to their interdependent effects, but this is sometimes difficult to achieve due to their wide distribution across all food groups; only a very balanced diet can provide all B vitamins in sufficient quantities. Indeed, large nutrition studies consistently reveal clear gaps in their supply.

The Seven B Vitamins in B Complex Sensitive

  • Thiamine (B1) is involved in energy production as well as the normal functioning of the nervous system and brain.
  • Riboflavin (B2) plays a role in energy production, the reduction of fatigue and in maintaining healthy skin and mucous membranes as well as in the protection of cells and DNA against oxidative stress.
  • Nicotinamide (B3) contributes to the regulation of energy and fatigue and is needed for the function of the nervous system, brain, skin and mucous membranes as well as being involved in serotonin and melatonin synthesis.
  • Pantothenic acid (B5) plays a role in energy production in the mitochondria and is required for the synthesis of protein, cholesterol, steroid hormones and neurotransmitters as well as for the metabolism of vitamins A and D.
  • Pyridoxine (B6) contributes to erythropoiesis and supports energy metabolism, hormone activity and the immune and nervous systems as well as playing a crucial role in amino acid metabolism.
  • Biotin (B7) contributes to the maintenance of normal skin, mucous membranes and hair as well as to the normal functioning of energy metabolism, the nervous system and macronutrient metabolism.
  • Folic acid (B9) plays a role in cell division, blood formation and amino acid and homocysteine metabolism as well as being essential for healthy pregnancies.
  • Vitamin B12 (cobalamin) is required for erythropoiesis and for building DNA and proteins.

Important Cofactors in B Complex Sensitive

In addition to the eight essential B-vitamins, there are several other vitamin-like nutrients that closely interact with B-vitamins as co-factors. These compounds were previously considered part of the B-vitamin group.

  • Choline (formerly known as Vitamin B4) is mainly found in the form of phosphatidylcholine (lecithin) and acetylcholine.
  • Inositol (formerly known as Vitamin B8) is predominantly found in the brain, liver, and kidneys.

The Amino Acids in B Complex Sensitive

In addition to the B vitamins, this complex supplies the three important amino acids taurine, L-glycine and L-glutamine. These amino acids are required for the synthesis of glutatione, a tripeptide and the body's central antioxidant, from cysteine (from taurine), L-glutamine and L-glycine.

Health Benefits of B Vitamins

According to the European Food Safety Authority (EFSA), B vitamins contribute to:

  • Maintaining normal skin and mucous membranes
  • Maintaining normal hair
  • Maintaining normal cognitive function
  • Normal macronutrient metabolism
  • Normal energy metabolism
  • Normal functioning of the nervous system
  • Normal heart function
  • Maintaining normal iron metabolism
  • Maintaining normal red blood cells
  • Protecting DNA, proteins and lipids from oxidative stress
  • Cell division
  • Maintaining normal cysteine synthesis
  • Maintaining normal amino acid synthesis


Recommended Dosage

Take 1 capsule daily with food and 200ml water.

Daily Requirements

The official daily requirement (NRV) for each B vitamin can be found below:

  • 1.1mg vitamin B1
  • 1.4mg vitamin B2
  • 16mg vitamin B3
  • 6mg vitamin B5
  • 1.4mg vitamin B6
  • 50µg biotin
  • 200µg folate
  • 2.5µg vitamin B12

Daily Cofactor Requirements

There are no official requirements for choline, inositol or betaine. All three can be synthesised in the body, so many people cover their daily needs endogenously. The following recommendations for dietary supplementation are stated in the literature:

  • Choline: 400mg (EFSA)/550mg (DGK)
  • Inositol: 2,000mg
  • Betaine/TMG: 500mg–2,000mg

Food Supplement

Do not exceed the recommended dose. Food supplements cannot replace a balanced and varied diet. Keep out of reach of children.


Store in a cool, dry place away from direct sunlight and heat.


Ingredients: Taurine, L-Glycine, L-Glutamine, Calcium D-Pantothenate, Pyridoxal-5'-Phosphate Monohydrate, Riboflavin 5'-Phosphate Sodium, Myo-Inositol, Thiamine HCl, Nicotinamide, CDP-Choline, D-Biotin, Adenosylcobalamin.
Capsule shells: Hydroxypropyl Methylcellulose.
Contains: 90 capsules

Ingredients/Capsule % NRV*
Vitamin B1 (Thiamine HCl) 25mg 2,273%
Vitamin B2 (R5P/FMN, bioactive) 20mg 1,429%
Vitamin B3 (bioactive) 25mg 156%
Vitamin B5 (bioactive) 50mg 833%
Vitamin B6 (P5P, bioactive) 20mg 1,429%
D-Biotin B7 (bioactive) 500µg 1,000%
Vitamin B12 (bioactive) 300µg 12,000%
CDP-Choline (bioactive) 10mg -**
Myo-Inositol (bioactive) 25mg -**
Taurine 200mg -**
L-Glycine 150mg -**
L-Glutamine 150mg -**

* Nutrient Reference Value
** no reference available


Neben Cholin und Inositol gibt es zwei weitere wichtige Kofaktoren:

  • Betain (als Trimethylglycin/TMG) eine weitere, aktivierte Form von Cholin.
  • PABA (ehemals Vitamin B10) fungiert als Coenzym und ist über das Vitamin B9 an der Bildung der roten Blutkörperchen beteiligt.

Product Details

German Pharmaceutical Number (PZN) 16850367
Production In-house production in Europe, bottling and encapsulation in the EU according to HACCP, GMP and ISO 22000:2018 standards
Finished products packaged in amber glass jars and stored in non-toxic containers
Shipping in mineral oil-free boxes
Capsules Plant-based cellulose (HPMC). Vegan
Premium HPMC quality: Free from controversial additives such as carrageenans and PEG
Packaging Amber glass jar to protect against light and oxidation (free from plasticisers and BPA)
To Reuse Remove product label by soaking the jar in warm water for 5 minutes. Glue residue can be removed with dish soap.

Laboratory Tests

The purity of our formulas is important to us. This is why we have both our raw ingredients as well as our finished products extensively tested by independent laboratories to confirm purity and active ingredient content. Here, we have provided the results of some of the tests carried out on this product.

Sunday Natural

Our Philosophy

For thousands of years, cultures all over the world have been using medicinal plants and nutritious foods to naturally foster and maintain vitality and good health.

With our products, we try to emulate this ancient wisdom as much as possible.

Consequently, our philosophy is simple: everything we do meets the highest standards of quality and purity; our focus is on organic and natural ingredients.

We follow this philosophy with meticulous care on all levels and down to every last detail.

Learn more.

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