Bioactive B Complex
With Cofactors


High-dose, bioactive B-complex with all eight B vitamins + three cofactors, including a total of 300µg of bioactive vitamin B12 from all three natural cobalamins. Supplies folate from our Complex Ultra (Quatrefolic® + Magnafolate®), vitamin B6 in the form of P5P and five different active ingredients of B12 from our MH3A® formula. All B vitamins in highly bioavailable and ultra-pure forms, plus cofactors: CDP-choline, myo-inositol and TMG/betaine. Vegan, no additives. Laboratory tested. 100 capsules
  • Premium, high-dose complex supplying all eight B vitamins plus three cofactors
  • Directly bioactive forms
  • Vitamin B12 from our MH3A® formula: contains all 3 natural and bioactive forms of B12
  • Folate from a bioactive folate complex: Quatrefolic® + Magnafolate®
  • Vitamin B6 in the form of directly bioactive P5P
  • Three important cofactors: active CDP-choline, TMG betaine and myo-inositol
  • All vitamins optimally bioavailable
  • Supports energy and iron metabolism, amino acid synthesis, mucous membranes, heart function, the nervous system, skin, hair and psyche as well as contributing to cell division and the protection of cells against oxidative stress
  • No additives
  • Ultra-pure, vegan capsule shells made from plant-based cellulose (HPMC), free from PEG and carrageenans
100 capsules

Delivery : 1–3 business days

Incl. VAT, excl. Shipping

€367.00 / 1kg
In stock

Premium Bioactive Ingredients

  • High-dose B complex with all eight B vitamins, plus three cofactors
  • Patented, pharmaceutical grade active ingredients: ultra pure and directly bioactive
  • Bioactive vitamin B12 from our MH3A® formula
  • All 3 natural and bioactive forms of vitamin B12
  • Bioactive folate complex from 2 patented forms of L-methylfolate (Quatrefolic® + Magnafolate®)
  • Vitamin B1 in the form of thiamine HCl
  • Vitamin B2 in the form of bioactive riboflavin 5′-phosphate
  • Vitamin B3 in the form of bioactive nicotinamide (flush free)
  • Vitamin B5 in the form of bioactive pantothenate
  • Vitamin B6 in the form of bioactive pyridoxal-5′-phosphate (P5P)
  • D-biotin
  • Three important cofactors: choline, betaine and inositol, in highly effective, bioidentical forms
  • All vitamins optimally bioavailable

How are we different?

Every B vitamin occurs in a variety of chemical forms. These can be divided into two subcategories: the synthetic forms, which cannot be found in nature and cannot be utilised by the body without first being converted, and the directly active, bioidentical forms, which have an immediate effect in the body. In our B Complex Forte, we use only the optimally bioavailable active and bioidentical forms, which the body can use directly. The only exception is vitamin B1, which in its active form is not permitted as a food supplement in Germany.

Some of the B vitamins, such as vitamin B12 and folic acid, have several naturally occurring forms:

Although standard practice to supply vitamin B12 in an isolated, synthetic context, our pioneering MH3A® formula offers the vitamin in the same way as it occurs in food: as a mixture of all three natural and bioactive forms, which allows the natural synergistic effects between them to occur (they each fulfil completely different tasks in the body and have different focal points of action). Our MH3A® formula contains these three forms of vitamin B12 in an equal ratio, spread across a total of five active forms of B12. This formula thus provides a foundational supply of vitamin B12 as found in nature, where all three forms are always found in a harmonious combination, both in our bodies and in the foods we eat. In contrast, the majority of products available on the market contain only one of the three B12 active ingredients: either methylcobalamin, hydroxocobalamin or adenosylcobalamin.

Conventional folic acid, which is used in many food supplements, is an artificial, synthetic product which cannot be utilised directly by the body; synthetic folic acid must first be converted to active folate in the body, a process requiring cofactors and enzymes which are not necessarily always in sufficient supply. Our unique folate complex consists of a combination of two bioactive, patented forms of L-methylfolate: the glucosamine salt Quatrefolic® and the highly bioavailable calcium salt Magnafolate® Pro, both of which provide 99.9% pure L-methylfolate. They both offer fast and effective absorption of the bioactive L-5-MTHF, with the form offering the better absorption of the two differing from person to person. Our folate complex thus ensures that the body is always supplied with sufficient folate in an ideal form.

The rest of the B vitamins in this complex are likewise included in their active forms, including vitamin B6 in the form of P5P (pyridoxal-5′-phosphate) and vitamin B2 in the form of R5P/FMN (riboflavin 5′-phosphate sodium).

In addition to the 8 vitamins forming the B complex, we have included 3 important cofactors (which for many years were considered B vitamins themselves): choline (formerly vitamin B4) in the form of CDP-choline, betaine/TMG (methyl choline) and myo-inositol (formerly vitamin B8).

For the capsule shells we use custom-made HPMC capsules that, unlike most other HPMC and pullulan capsules on the market, are 100% free from controversial additives such as carrageenans and PEG. We then package this product in environmentally friendly amber glass.


  • Premium active ingredients in their purest form
  • Sourced directly from the world’s best producers
  • Our select raw materials are the basis of all our formulations
  • Complete avoidance of all unnecessary additives and adjuvants
  • Exclusive use of valuable natural ingredients for additives
  • We voluntarily declare all ingredients
  • All extractions performed without the use of chemical solvents
  • Custom production when necessary, in order to achieve the highest possible level of purity
  • Independent laboratory testing available on product pages
  • Raw materials sourced only from premium suppliers who are committed to fair working conditions
  • Amber glass and compostable pouches used for packaging
  • Vegan capsule shells, free from PEG and carrageenans
  • Packaged in the EU according to HACCP, GMP and ISO 22000:2018 standards
  • Stored in non-toxic containers
  • Shipped in mineral oil-free boxes
  • All products guaranteed 100% free from magnesium stearate, silicon dioxide, nanoparticles (no legal opportunism), genetic engineering, artificial colours and flavours, titanium dioxide and added sugar & sweeteners


B Vitamins

The B vitamin group includes eight water-soluble essential nutrients: vitamins B1, B2, B3, B5, B6, B12, biotin and folic acid. Unlike many vitamins, B vitamins cannot be stored in the body over a long period of time and must therefore be obtained daily through food. The only exception is vitamin B12, which can be stored in the liver.

It is crucial to ensure a balanced intake of all B vitamins due to their interdependent effects, but this is sometimes difficult to achieve due to their wide distribution across all food groups; only a very balanced diet can provide all B vitamins in sufficient quantities. Indeed, large nutrition studies consistently reveal clear gaps in their supply.

High-Dose B Complex Forte with Three Cofactors

Directly bioactive B vitamins provide optimal bioavailability and efficacy to the body. The B vitamins included here are in highly effective, bioidentical forms as well as in active coenzyme forms. The addition of choline, betaine, inositol and PAPA, cofactors which were formerly considered B vitamins, further increases their bioavailability and efficacy.

  • Thiamine (B1) is involved in energy production as well as the normal functioning of the nervous system and brain.
  • Riboflavin (B2) plays a role in energy production, the reduction of fatigue and in maintaining healthy skin and mucous membranes as well as in the protection of cells and DNA against oxidative stress.
  • Nicotinamide (B3) contributes to the regulation of energy and fatigue and is needed for the function of the nervous system, brain, skin and mucous membranes as well as being involved in serotonin and melatonin synthesis.
  • Pantothenic acid (B5) plays a role in energy production in the mitochondria and is required for the synthesis of protein, cholesterol, steroid hormones and neurotransmitters as well as for the metabolism of vitamins A and D.
  • Pyridoxine (B6) contributes to erythropoiesis and supports energy metabolism, hormone activity and the immune and nervous systems as well as playing a crucial role in amino acid metabolism.
  • Folic acid (B9) plays a role in cell division, blood formation and amino acid and homocysteine metabolism as well as being essential for healthy pregnancies.
  • Vitamin B12 (cobalamin) is required for erythropoiesis and for building DNA and proteins.

Three Important Cofactors

There are several vitamin-like nutrients that work together with the B vitamins as cofactors. Due to their close interaction, these compounds were considered B vitamins themselves until recently.

  • Choline (formerly vitamin B4) is part of acetylcholine, one of the most important neurotransmitters in humans, and supports fat and homocysteine metabolism as well as healthy liver function.
  • Betaine (in the form of trimethylglycine/TMG) is an activated form of choline and plays an important role in the methylation cycle and in homocysteine metabolism.
  • Inositol (formerly vitamin B8), part of the cell membrane, is a precursor of many chemical messengers and plays an important role in cell metabolism as a secondary messenger.

Health Benefits of B Vitamins

According to the European Food Safety Authority (EFSA), B vitamins contribute to:

  • Maintaining normal skin and mucous membranes
  • Maintaining normal hair
  • Maintaining normal cognitive function
  • Normal macronutrient metabolism
  • Normal energy metabolism
  • Normal functioning of the nervous system
  • Normal heart function
  • Maintaining normal iron metabolism
  • Maintaining normal red blood cells
  • Protecting DNA, proteins and lipids from oxidative stress
  • Cell division
  • Maintaining normal cysteine synthesis
  • Maintaining normal amino acid synthesis


Recommended Dosage

Take 1 capsule daily with food and 200ml water.

Daily Requirements

The official daily requirement (NRV) for each B vitamin can be found below:

  • 1.1mg vitamin B1
  • 1.4mg vitamin B2
  • 16mg vitamin B3
  • 6mg vitamin B5
  • 1.4mg vitamin B6
  • 50µg biotin
  • 200µg folate
  • 2.5µg vitamin B12

Daily Cofactor Requirements

There are no official requirements for choline, inositol or betaine. All three can be synthesised in the body, so many people cover their daily needs endogenously. The following recommendations for dietary supplementation are stated in the literature:

  • Choline: 400mg (EFSA)/550mg (DGK)
  • Inositol: 2,000mg
  • Betaine/TMG: 500mg–2,000mg


Contains potent methyl donors. For individuals who overmethylate, we recommend our B Complex Sensitive.

Food Supplement

Do not exceed the recommended dose. Food supplements cannot replace a balanced and varied diet. Keep out of reach of children.


Store in a cool, dry place away from direct sunlight and heat.


Ingredients: Nicotinamide, Calcium D-Pantothenate, TMG/Betaine, Thiamine HCl, Pyridoxal-5'-Phosphate Monohydrate, Riboflavin 5'-Phosphate Sodium, Myo-Inositol, CDP-Choline, D-Biotin, 6S-5-Methyltetrahydrofolate Glucosamine Salt (Quatrefolic®), 6S-5-Methyltetrahydrofolate Calcium Salt (Magnafolate® Pro), Methylcobalamin, Hydroxocobalamin, Adenosylcobalamin.
Capsule shells: Hydroxypropyl Methylcellulose.
100 capsules

Ingredients/Capsule % NRV*
Vitamin B1 (Thiamine HCl)  40mg 3,636%
Vitamin B2 (R5P/FMN, bioactive) 20mg 1,429%
Vitamin B3 (bioactive) 100mg 625%
Vitamin B5 (bioactive) 50mg 833%
Vitamin B6 (P5P, bioactive) 20mg 1,429%
D-Biotin B7 (bioactive) 500µg 1,000%
Folate B9 (from Quatrefolic®, Magnafolate® Pro) 400µg 200%
Vitamin B12 (MH3A®) 300µg 12,000%
CDP-Choline (bioactive) 10mg -**
TMG/Betaine (bioactive) 50mg -**
Myo-Inositol (bioactive) 25mg -**

* Nutrient Reference Value
** no reference available



Another important cofactor of 8 essential B vitamins is PABA (formerly vitamin B10). As a building block of folic acid, PABA is involved in processes such as the metabolism of protein and the formation of red blood cells.

Product Details

German Pharmaceutical Number (PZN) 16850350
Production In-house production in Europe, bottling and encapsulation in the EU according to HACCP, GMP and ISO 22000:2018 standards
Finished products packaged in amber glass jars and stored in non-toxic containers
Shipping in mineral oil-free boxes
Capsules Plant-based cellulose (HPMC). Vegan
Premium HPMC quality: Free from controversial additives such as carrageenans and PEG
Packaging Amber glass jar to protect against light and oxidation (free from plasticisers and BPA)
To Reuse Remove product label by soaking the jar in warm water for 5 minutes. Glue residue can be removed with dish soap.

Sunday Natural

Our Philosophy

For thousands of years, cultures all over the world have been using medicinal plants and nutritious foods to naturally foster and maintain vitality and good health.

With our products, we try to emulate this ancient wisdom as much as possible.

Consequently, our philosophy is simple: everything we do meets the highest standards of quality and purity; our focus is on organic and natural ingredients.

We follow this philosophy with meticulous care on all levels and down to every last detail.

Learn more.

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