High-Dose
Vitamin B6
Bioactive PLP

Bundle

SKU
5268-bundle
Directly bioactive vitamin B6 in the form of PLP (pyridoxal 5'-phosphate). High-dose vitamin B6, 25mg per capsule, suitable for individuals with very high vitamin B6 requirements. With the addition of premium acacia fibre as a natural filler, a well tolerated, natural and sustainably cultivated food source for intestinal bacteria. Vegan, no additives. 2x120 capsules
  • High-dose vitamin B6: 25mg per capsule
  • Ideal for individuals with high vitamin B6 requirements
  • Vitamin B6 in the form of bioactive PLP (pyridoxal 5'-phosphate)
  • PLP is the directly bioactive coenzyme form of vitamin B6
  • Vitamin B6 supports the nervous and immune system and contributes to energy, protein, glycogen and homocysteine metabolism and cysteine synthesis
  • Vitamin B6 aids in the formation of red blood cells, reduces tiredness and fatigue and regulates hormone activity as well as the psyche
  • Natural acacia fibre as the only other ingredient
Customize High-Dose<br>Vitamin B6<br>Bioactive PLP
2 x High-Dose Vitamin B6 Bioactive PLP   + €0.00

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€18.80 €19.80

2x120 capsules
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Delivery : 1–3 business days

Incl. VAT, excl. Shipping

SKU
5268-bundle
€310.23 / 1kg

Premium Bioactive Ingredients

  • Vitamin B6 in the form of bioactive PLP (pyridoxal 5'-phosphate)
  • High-dose vitamin B6: 25mg PLP per capsule
  • PLP is the directly bioavailable coenzyme form of vitamin B6, required in numerous metabolic reactions
  • Ultra-pure vitamin B6, 100% vegan
  • High-quality, natural filler: acacia fibre cultivated without the use of plant protection products

How are we different?

Vitamin B6 is present as a variety of different active compounds. Pyridoxine, which is the form that most manufacturers use, is not actually biologically active until converted by the body. We have therefore chosen pyridoxal 5'-phosphate (PLP) as the active ingredient in our formulation, the directly active coenzyme form of vitamin B6, which the body can use directly in all important metabolic pathways.

Our premium PLP is a pure, high-quality and vegan active ingredient with the highest possible bioavailability.

The only other ingredient is premium acacia fibre, cultivated without the use of plant protection products. In contrast to microcrystalline cellulose, a widely used synthetic filler often mixed with nanoparticles, gum arabic is a natural, fibre-rich food. Our fair trade acacia gum is climate neutral and is sustainably cultivated to conserve resources.

For the capsule shells we use custom-made HPMC capsules that, unlike most other HPMC and pullulan capsules on the market, are 100% free from controversial additives such as carrageenans and PEG. We then package this product in environmentally friendly amber glass.

truecleanlabel

  • Premium active ingredients in their purest form
  • Sourced directly from the world’s best producers
  • Our select raw materials are the basis of all our formulations
  • Complete avoidance of all unnecessary additives and adjuvants
  • Exclusive use of valuable natural ingredients for additives
  • We voluntarily declare all ingredients
  • All extractions performed without the use of chemical solvents
  • Custom production when necessary, in order to achieve the highest possible level of purity
  • Independent laboratory testing available on product pages
  • Raw materials sourced only from premium suppliers who are committed to fair working conditions
  • Amber glass and compostable pouches used for packaging
  • Vegan capsule shells, free from PEG and carrageenans
  • Packaged in the EU according to HACCP, GMP and ISO 22000:2018 standards
  • Stored in non-toxic containers
  • Shipped in mineral oil-free boxes
  • All products guaranteed 100% free from magnesium stearate, silicon dioxide, nanoparticles (no legal opportunism), genetic engineering, artificial colours and flavours, titanium dioxide and added sugar & sweeteners

Effects

Vitamin B6 (Pyridoxine)

Vitamin B6 (pyridoxine) is the precursor of pyridoxal 5'-phosphate (PLP), one of the most important coenzymes in humans. As an active coenzyme form of vitamin B6, PLP enables about 100 enzymatic reactions and plays a central role in the metabolism of amino acids.

Vitamin B6 supports the breakdown of homocysteine and contributes to the normal synthesis of cysteine, an amino acid which serves as a central building block of important compounds such as coenzyme A, creatine, glutathione and taurine.

Vitamin B6 is also involved in the synthesis of the neurotransmitters serotonin, noradrenaline, dopamine and GABA. In addition, by modulating the effect of testosterone and oestrogen, vitamin B6 makes an important contribution to normal mental function and a healthy nervous system through these steroid hormones.

The influence of vitamin B6 in the nervous system extends to the synthesis of important components of the cell membrane, including myelin, a protective nerve layer, as well as phospholipids and sphingolipids.

Vitamin B6 is also important for energy metabolism, as it is involved in the metabolism of protein and glycogen. Glycogen is a carbohydrate that serves as an energy store in cells.

Directly Bioactive Vitamin B6 in the Form of PLP

In the form of pyridoxine, vitamin B6 does not have any direct biological activity. It must first be converted by the body into bioactive pyridoxal 5'-phosphate (PLP), a coenzyme form of vitamin B6, in order to be metabolically active.

Health Benefits of Vitamin B6

According to the European Food Safety Authority (EFSA), vitamin B6 contributes to:

  • Normal energy metabolism
  • Normal protein and glycogen metabolism
  • Normal functioning of the nervous system
  • Normal immune system functioning
  • Normal mental function
  • Hormonal activity regulation
  • Reducing tiredness and fatigue
  • Normal red blood cell formation
  • Normal homocysteine metabolism
  • Normal cysteine synthesis

Dosage

Recommended Dosage

Take 1 capsule (25mg vitamin B6 in the form of PLP) daily with 200ml water and a meal.

Daily Requirements

The requirement for vitamin B6 is between 1.2-1.8mg daily and increases according to protein intake.

Larger quantities of vitamin B6 are required by individuals who are pregnant, breastfeeding or of advanced age, during sports or stressful periods and with high-protein diets. Smoking and alcohol consumption, as well as many medications, further increase B6 needs. Moreover, this vitamin is very sensitive to heat and can be disintegrated during cooking or frying.

Food Supplement

Do not exceed the recommended dose. Food supplements cannot replace a balanced and varied diet. Keep out of reach of children.

Storage

Store in a cool, dry place away from direct sunlight and heat.

Contents

Ingredients: Acacia Fibre, Vitamin B6 (Pyridoxal Phosphate).
Capsule Shells: Hydroxypropyl Methylcellulose.
Contains: 120 capsules

Ingredients/Capsule % NRV*
Vitamin B6 (PLP) 25mg 1,768%

* Nutrient Reference Value

Per capsule: 25mg vitamin B6
In total: 3,000mg vitamin B6/jar 

Cofactors

All eight essential B vitamins work together. Numerous metabolic processes in the body require them; they can only achieve optimal functionality if each vitamin is in sufficient supply. Therefore, in many cases, it makes sense to supplement these vitamins together.

Magnesium, iron and zinc support the effects of vitamin B6.
Vitamin B6 is particularly synergistic with folate and vitamin B12.
Vitamin B2 deficiency increases the excretion of vitamin B6.
Nicotinic acid (B3) acts as an antagonist in high doses.
Coenzyme Q10 and vitamin B6 work together synergistically.
Vitamin B6 works together with vitamin B12, folate and betaine/choline to break down homocysteine.

Product Details

German Pharmaceutical Number (PZN) 16850373
Origin Filler: Premium acacia fibre from Africa, gently processed in France
Production In-house production in Europe, bottling and encapsulation in the EU according to HACCP, GMP/ISO 22000:2018 standards
Finished products packaged in amber glass jars and stored in non-toxic containers
Shipping in mineral oil-free boxes
Capsules Plant-based cellulose (HPMC). Vegan
Premium HPMC quality: Free from controversial additives such as carrageenans and PEG
Packaging Amber glass jar to protect against light and oxidation (free from plasticisers and BPA)
To Reuse Remove product label by soaking the jar in warm water for 5 minutes. Glue residue can be removed with dish soap

Laboratory Tests

The purity of our formulas is important to us. This is why we have both our raw ingredients as well as our finished products extensively tested by independent laboratories to confirm purity and active ingredient content. Here, we have provided the results of some of the tests carried out on this product.

Sunday Natural

Our Philosophy

For thousands of years, cultures all over the world have been using medicinal plants and nutritious foods to naturally foster and maintain vitality and good health.

With our products, we try to emulate this ancient wisdom as much as possible.

Consequently, our philosophy is simple: everything we do meets the highest standards of quality and purity; our focus is on organic and natural ingredients.

We follow this philosophy with meticulous care on all levels and down to every last detail.

Learn more.

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